In addressing the September 2007 theme—the parental-fetal disconnect—contributors explore the physician’s role in managing conflicts between the behavior and wishes of parents and the best interest of the fetus. Using assisted reproductive technology (ART), it is now possible to select embryos with specific traits for implantation, donate sperm and eggs posthumously, and bear children after menopause. September authors sort out whether these and other ART-related possibilities serve the best interest of the offspring.